Titlebook: cGMP: Generators, Effectors and Therapeutic Implications; Harald H. H. W. Schmidt,Franz Hofmann,Johannes-Pet Book 2009 Springer-Verlag Ber

Moderate

NO and sGC-Stimulating NO Donorsed by activation of soluble guanylyl cyclase (sGC) in target tissues. The aim of this chapter is to encapsulate the functions of NO in mammalian biology, tied to the chemistry of this unusual signalling entity. The experimental usefulness and therapeutic potential of the most widely utilised NO dono

Watemelon

甜食

NO- and Haem-Independent Soluble Guanylate Cyclase Activatorsformation of the strong intermediate oxidant, peroxynitrite. Under these conditions, endothelial and vascular dysfunction develops, culminating in different cardio-renal and pulmonary-vascular diseases. Substituting NO with organic nitrates that release NO (NO donors) has been an important principle

Ataxia

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爱哭

勋章

cGMP-Dependent Protein Kinase as a Modifier of Behaviour effects of PKG on behaviour have been studied in diverse taxa from perspectives as varied as ethology, evolution, genetics and neuropharmacology. The genetic variation of the . gene, ., has provided a fertile model for examining natural variation in a single major gene influencing behaviour. Concur

BARGE

BOON

–scent

Function and Dysfunction of Mammalian Membrane Guanylyl Cyclase Receptors: Lessons from Genetic Mousossification. GC-C mediates the effects of guanylin and uroguanylin on intestinal electrolyte and water transport and epithelial cell growth and differentiation. GC-E and GC-F are colocalized within the same photoreceptor cells of the retina and have an important role in phototransduction. Finally,