| 书目名称 | cGMP: Generators, Effectors and Therapeutic Implications | | 编辑 | Harald H. H. W. Schmidt,Franz Hofmann,Johannes-Pet | | 视频video | | | 概述 | Includes supplementary material: | | 丛书名称 | Handbook of Experimental Pharmacology | | 图书封面 |  | | 描述 | .After the discovery of endogenous NO formation in the late ‘80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.. | | 出版日期 | Book 2009 | | 关键词 | Regulation; blood cell; cGMP; guanylyl cyclase; phosphodiesterase; physiology; protein kinase G | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-540-68964-5 | | isbn_softcover | 978-3-642-08848-3 | | isbn_ebook | 978-3-540-68964-5Series ISSN 0171-2004 Series E-ISSN 1865-0325 | | issn_series | 0171-2004 | | copyright | Springer-Verlag Berlin Heidelberg 2009 |
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发表于 2025-3-21 19:07:47
