Titlebook: Current Perspectives in microRNAs (miRNA); Shao-Yao Ying Book 2008 Springer Science+Business Media B.V. 2008 DNA.Microarray.RNA Splicing.S

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Role of Repeat-Associated MicroRNA (ramRNA) in Fragile X Syndrome (FXS),lated neurodegeneration. Based on this model, we found that ramRNA-induced DNA methylation of the . 5′-UTR CGG trinucleotide repeat expansion is central to FXS etiology. This epigenetic modification leads to physical, neurocognitive and emotional characteristics linked to the transcriptional . gene

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Expression and Function of microRNAs in Chronic Myeloid Leukemia,ses proliferation and enhances sensitivity to imatinib induced cell death. Furthermore, reporter assays using luciferase genes with specific miRNA binding sites in the 3′ untranslated region were used to specifically inhibit miRNA function by so called antagomirs. Finally, strategies to induce stabl

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microRNA in Cutaneous Wound Healing, areas related to cutaneous wound healing are addressed: skin structure and function, stem cell biology, infection, immunity, inflammation, angiogenesis and extracellular matrix. Furthermore, we discuss opportunities for miRNA-based therapeutics in addressing chronic wounds as a major public health

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Spezifische Konflikte in Ost und West,previously reported. Because the intronic miRNA-mediated gene silencing pathway is tightly regulated by multiple intracellular surveillance systems, including Pol-II transcription, RNA splicing, exosome digestion and NMD processing, the current findings underscore the fact that intronic miRNA agents

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Cliquentypen in den Untersuchungsregionen,n conclusion, dynamic changes in miRNA expression occurred during erythroid differentiation, with an overall increase in the levels of miRNAs upon terminal differentiation of erythroid cells. MiR-451 may play a role in promoting erythroid differentiation.

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Spezifische Konflikte in Ost und West,for diverse diseases, especially for cancers. Even more, some indirect evidences show that the initiation and maintenance of cancer stem cells may be under their controls. Thus accumulated understanding of microRNAs functions in different biological processes will bring new approaches for regenerati

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