Titlebook: Current Perspectives in microRNAs (miRNA); Shao-Yao Ying Book 2008 Springer Science+Business Media B.V. 2008 DNA.Microarray.RNA Splicing.S

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MicroRNA Profiling in CNS Tissue Using Microarrays,S. They are involved in repressing gene expression by complementary hybridization to cognate protein-coding mRNAs. The likely involvement of miRNAs in disease processes requires both accurate detection and expression analysis strategies. In comparison to conventional methodologies to study miRNA exp

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MicroRNA and Erythroid Differentiation,sion profiles in erythroid cells at different stages of maturation and the regulation of erythroid differentiation by specific miRNAs. We found that more than one hundred miRNAs were expressed in erythroid cells. The majority of them showed changes in their expression levels during erythroid differe

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MicroRNA in Muscle Development and Function,ally. The emerging field of miRNA biology has begun to unravel roles for these regulatory molecules in a range of biological functions, including cell proliferation, differentiation and development. The molecular events that regulate cardiac and skeletal muscle development, as well as in muscle-rela

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MicroRNAs and Regenerative Medicine,ne expression that were identified only decades ago and recently have been shown potential therapeutic value for diverse diseases. Thus, combination of microRNAs and regenerative medicine become an emerging interdisciplinary medical field that may yield new exciting possibilities for clinical medici

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Role of mir-302 MicroRNA Family in Stem Cell Pluripotency and Renewal,ry difficult to maintain the purity and pluripotency of these hES cells. In a fertilized egg, maternal materials naturally maintain stem cell renewal and totipotency before the 128-cell stage of embryonic development. Mouse oocytes lacking Dicer, a conserved ribonuclease required for microRNA (miRNA

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Epigenetic Regulation of miRNA in Stem Cells,emplifies the critical role of epigenetic regulation in modulating the expression of common genomes so as to link cellular genotype with phenotype. Various types of epigenetic regulation in the context of stem cells, and in particular that of epigenetic regulation of non-coding microRNA, hold signif

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Identification of Cellular Targets for Virally-Encoded miRNAs by Ectopic Expression and Gene Expresyomaviruses [12, 68, 69, 82, 92]. MiRNAs are short 22 ± 3 nt RNA molecules that post-transcriptionally regulate gene expression by binding to 3′ UTRs of target mRNAs thereby inducing translational silencing and/or mRNA degradation [1, 3]. Because miRNAs require only limited complementarity, miRNA ta