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Titlebook: Current Perspectives in microRNAs (miRNA); Shao-Yao Ying Book 2008 Springer Science+Business Media B.V. 2008 DNA.Microarray.RNA Splicing.S

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书目名称Current Perspectives in microRNAs (miRNA)
编辑Shao-Yao Ying
视频video
概述Novel non-coding RNA mechanisms.Novel applications of microRNAs.Up-to-day findings in microRNA research.New concept of microRNA functions in animals and plants.Detailed introduction of different micro
图书封面Titlebook: Current Perspectives in microRNAs (miRNA);  Shao-Yao Ying Book 2008 Springer Science+Business Media B.V. 2008 DNA.Microarray.RNA Splicing.S
描述.Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species found in vertebrates and many more new miRNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide sig
出版日期Book 2008
关键词DNA; Microarray; RNA Splicing; SNP; cells; gene expression; genes; miRNAs; physiology; tissue
版次1
doihttps://doi.org/10.1007/978-1-4020-8533-8
isbn_softcover978-90-481-7903-9
isbn_ebook978-1-4020-8533-8
copyrightSpringer Science+Business Media B.V. 2008
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Personbezogenes Wissensmanagement, processing of microRNA transcripts involves the activities of two RNase III enzymes Drosha and Dicer. In this study we analyzed structural features of human microRNA precursors that make these transcripts Drosha and Dicer substrates. The structures of minimal functional primary precursors (pri-micr
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Cliquentypen in den Untersuchungsregionen,ife sciences. Small RNAs, namely small interfering RNA (siRNA) and microRNA (miRNA), not only play key roles in down regulating gene expression, controlling growth and development, stress response, and various diseases, but also serve as essential tools for the study of gene functions. In this chapt
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Spezifische Konflikte in Ost und West,kin care ., particularly for hyperpigmentation treatment and aging prevention. For example, tyrosinase (Tyr), a melanocytic membrane-bound glycoprotein, is the rate-limiting enzyme critical for melanin (black pigment) biosynthesis in skins and hairs. There are over 54 native microRNA capable of targ
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