Titlebook: Catalytic RNA; Fritz Eckstein,David M. J. Lilley Book 1997 Springer-Verlag Berlin Heidelberg 1997 AIDS.HIV.Nucleotide.RNA.biology.catalysi

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Structural Analysis of the Bacterial Ribonuclease P RNA,e tRNAs. The enzyme is present and essential in all cells and organelles that produce tRNA. RNase P is remarkable because of its composition: it is composed of RNA and protein subunits. The RNA moiety forms the catalytic center, so RNase P is intrinsically a ribozyme. The enzyme from a broad diversi

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大约冬季

时代错误

expeditious

The Hammerhead Ribozyme,mons 1992 and Bratty et al. 1993). Its two-dimensional representation (Fig. 1) has now been transformed into a three-dimensional model by the application of X-ray crystallography (Pley et al. 1994; Scott et al. 1995) (see also chapter by McKay), fluorescence resonance energy transfer (FRET) measurem

embolus

biosphere

Mechanistic Studies on Hammerhead Ribozymes, (Altman 1989; Cech 1989; Michel et al. 1989; Noller et al. 1992; Symons 1992; Bratty et al. 1993; Gesteland and Atkins 1993). Of all these catalytic RNAs, the hammerhead ribozyme is the smallest. Naturally occurring hammerhead ribozymes were identified initially within RNA viruses and they act in .

原谅

Hammerhead Ribozymes with Long Flanking Sequences: a Structural and Kinetic View, et al. 1982; Guerrier-Takada et al. 1983) in an intramolecular (in .) as well as an intermolecular (in .) reaction. All classes of ribozymes (for review, see Symons 1992; Cech 1993) recognize their target by duplex formation via complementary sequences and hydrolyze the cleavable motif after format

Cryptic

Design, Synthesis, and Function of Therapeutic Hammerhead Ribozymes, the function of RNA in chemistry, biology, and medicine. RNA traditionally was viewed as a passive molecule that only carries information or provides structure. It is now clear that RNA can act as an enzyme, capable of catalyzing not only RNA splicing and cleavage, but a diverse number of reactions

sterilization