Titlebook: Catalytic RNA; Fritz Eckstein,David M. J. Lilley Book 1997 Springer-Verlag Berlin Heidelberg 1997 AIDS.HIV.Nucleotide.RNA.biology.catalysi

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Efficacy of Hammerhead Ribozymes Targeting ,-Lactalbumin Transcripts: Experiments in Cells and Trann enzymatic reaction in which a target substrate is cleaved and the ribozyme itself is not altered during the reaction. Ribozyme-mediated cleavage in vitro was first demonstrated by Uhlenbeck (1987) and subsequently by Haseloff and Gerlach (1988).

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Nucleic Acids and Molecular Biologyhttp://image.papertrans.cn/c/image/222482.jpg

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Organized Crime in the 21st Centuryg and catalysis over the past 10 years. By 1985 the sequential steps in RNA self-splicing had been described (Zaug and Cech 1982) and the secondary structure common to group I introns had been determined (Davies et al. 1982; Michel et al. 1982; Waring and Davies 1984). Furthermore, several fungal mi

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Susan Watkinson,Swapna Naskar Williamsonions (Cech 1993). In vitro, these ribozymes carry out self-splicing via two consecutive transesterification reactions, leading to their own excision from a pre-messenger RNA and the ligation of the flanking exon sequences, generally, in the absence of protein (Cech 1990). This relatively complex pro

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Springer Series in Reliability Engineeringl RNA, led to a new aspect in studying RNA structure and function. Simple amino sugars were added to the list of components influencing catalytic RNAs. Although several experiments pointed to a direct interaction of antibiotics with the ribosomal RNA, the presence of ribosomal proteins excluded a sa

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