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Titlebook: Catalytic RNA; Fritz Eckstein,David M. J. Lilley Book 1997 Springer-Verlag Berlin Heidelberg 1997 AIDS.HIV.Nucleotide.RNA.biology.catalysi

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Stine Helene Falsig Pedersen,Diane L. Barberreplication of its causative agent, human immunodeficiency virus (HIV). Since the efforts of prophylactic vaccines have repeatedly failed, anti-viral strategies are now being aimed at direct inhibition of the virus or its replication. Infection by HIV leads to a progressive depletion of CD4. cells o
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https://doi.org/10.1007/978-3-642-61202-2AIDS; HIV; Nucleotide; RNA; biology; catalysis; chemistry; fungi; genetics; molecular biology; molecular genet
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978-3-540-62679-4Springer-Verlag Berlin Heidelberg 1997
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Catalytic RNA978-3-642-61202-2Series ISSN 0933-1891 Series E-ISSN 1869-2486
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Dynamics of a Group I Ribozyme Detected by Spectroscopic Methods,ed from the group I intron of . (Zaug et al. 1988; Kay and Inoue 1987) provides an excellent system for studying dynamics, since its secondary structure is known (Michel and Dujon 1983; Burke et al. 1987; Cech et al. 1994) and a good model is available for its three-dimensional structure (Michel and
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The Structure of Group I Ribozymes,ions (Cech 1993). In vitro, these ribozymes carry out self-splicing via two consecutive transesterification reactions, leading to their own excision from a pre-messenger RNA and the ligation of the flanking exon sequences, generally, in the absence of protein (Cech 1990). This relatively complex pro
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