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Titlebook: Catalytic RNA; Fritz Eckstein,David M. J. Lilley Book 1997 Springer-Verlag Berlin Heidelberg 1997 AIDS.HIV.Nucleotide.RNA.biology.catalysi

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书目名称Catalytic RNA
编辑Fritz Eckstein,David M. J. Lilley
视频video
丛书名称Nucleic Acids and Molecular Biology
图书封面Titlebook: Catalytic RNA;  Fritz Eckstein,David M. J. Lilley Book 1997 Springer-Verlag Berlin Heidelberg 1997 AIDS.HIV.Nucleotide.RNA.biology.catalysi
描述In recent years, unprecedented advances in many aspects of the molecular biology of nucleic acids have been witnessed. The area of RNA chemistry has undergone a kind of explosion, with a huge interest in RNA-mediated catalysis. At the same time, our structural understanding of DNA-protein interactions has increased enormously, and the related area of RNA-protein interactions is beginning to gather pace. This softcover edition from the successful series .Nucleic . .Acids and Molecular Biology. is devoted to the structure and mechanism of ribozymes, and their potential exploitation. The subject has both important evolutionary implications and potential practical application in the development of therapeutic agents for diseases such as AIDS.
出版日期Book 1997
关键词AIDS; HIV; Nucleotide; RNA; biology; catalysis; chemistry; fungi; genetics; molecular biology; molecular genet
版次1
doihttps://doi.org/10.1007/978-3-642-61202-2
isbn_softcover978-3-540-62679-4
isbn_ebook978-3-642-61202-2Series ISSN 0933-1891 Series E-ISSN 1869-2486
issn_series 0933-1891
copyrightSpringer-Verlag Berlin Heidelberg 1997
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https://doi.org/10.1007/978-3-031-22039-5Vol. This application has been successfully extended to the study of transgenic animals containing a hammerhead ribozyme gene targeted against the gene of interest (Heinrich et al. 1993; Zhao and Pick 1993; Efrat et al. 1994; Larsson et al. 1994; see also L’Huillier, this Vol.).
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Terminal Control of Multi-agent Systeme in the use of ribozymes with long-chain flanking sequences that have been expressed endogenously or transcribed enzymatically in vitro before being introduced into cells. Only rarely have short-chain and chemically synthesized ribozymes been used succesfully in living cells. Conversely, their stru
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Lecture Notes in Computer Scienceith protein enzymes has redefined the role that RNA may have played in early evolution (Cech 1993). Furthermore, these novel activities of RNA now permit us to contemplate the development of enzymatic RNA molecules as therapeutic entities for the treatment of human disease (Marschall et al. 1994; Ch
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Maria Stefanova,Stanislav Baklanovn enzymatic reaction in which a target substrate is cleaved and the ribozyme itself is not altered during the reaction. Ribozyme-mediated cleavage in vitro was first demonstrated by Uhlenbeck (1987) and subsequently by Haseloff and Gerlach (1988).
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