Overview: This book constitutes the refereed proceedings of the 14th International Conference on Large-Scale Scientific Computations, LSSC 2023, held in Sozopol, Bulgaria, during June 5–9, 2023. .The 49 full papers included in this book were carefully reviewed and selected from 61 submissions. They were organized in topical sections as follows: preconditioning and multilevel methods; fractures and mixed dimensional modeling: discretizations, solvers, and methodology; machine learning and model order reduction for large scale predictive simulations; fractional differential problems: theoretical
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