Titlebook: Smad Signal Transduction; Smads in Proliferati Peter ten Dijke,Carl-Henrik Heldin Book 2006 Springer Science+Business Media B.V. 2006 evolu

RADE

死亡

,Systems Biology Approaches to TGF-β/Smad Signaling,y relevant to ultimately reconciling and understanding the many diverse observations pertaining to TGF-β and Smads. Although this is still a nascent field, new tools and approaches have produced recent advances, particularly in mapping of signaling networks and in computational modeling of signaling

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低位的人或事

1567-2530 he first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue

臭了生气

Book 2006 are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue homeostasis. In a series of 22 cutting-edge chapters forward looking reviews of Smads are provided that cover their discovery, evolution, role

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Bereavement

Nucleocytoplasmic Shuttling of Smad Proteins, discusses the current models for the establishment of the Smads’ steady state distributions in the absence and the presence of a TGF-β-superfamily signal. Finally, we address the biological relevance of continuous nucleocytoplasmic shuttling for signaling by TGF-β superfamily members

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, TGF-β Signaling Pathways,interesting ligand, ., that does not appear to require conventional TGF-β superfamily receptors and Smads. In addition, two other TGF-β superfamily ligands have been identified. In some cases, aspects of TGF-β signaling have been modified in .