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Titlebook: Sex and Gender Differences in Pharmacology; Vera Regitz-Zagrosek Book 2012 Springer-Verlag Berlin Heidelberg 2012 adverse effects.drug dev

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Sex and Gender Differences in Cardiovascular Drug Therapyonary artery disease, hypertension, heart failure. Retrospective analysis of previously published drug trials revealed marked sex differences in efficacy and adverse effects in a number of cardiovascular drugs. This includes a higher mortality among women taking digoxin for heart failure, more torsa
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Sex and Gender Aspects in Anesthetics and Pain Medicationical differences present between men and women. Although in anesthesiology sex–gender aspects have attracted little attention, it has been reported that women have a greater sensitivity to the non-depolarizing neuroblocking agents, whereas males are more sensitive than females to propofol. It has be
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Adrenal Disordersuspected on clinical grounds, adrenal insufficiency has to be confirmed by inappropriately low serum cortisol with elevated adrenocorticotropin (ACTH) (in case of primary adrenal insufficiency). A morning plasma cortisol ≤3 μg/dl is indicative for adrenal failure, whereas a cortisol ≥19 μg/dl rules
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Book 2012iew on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effect
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imäre und sekundäre Form ist für die Behandlung von großer Bedeutung. Bei der primären MI ist ein Klappenanteil strukturell nicht funktionstüchtig und bedingt die Insuffizienz, am häufigsten ein Prolaps der Segel. Bei der sekundären MI ist die Klappe selbst intakt, aber eine zugrunde liegende Dilata
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