Titlebook: Sex and Gender Differences in Pharmacology; Vera Regitz-Zagrosek Book 2012 Springer-Verlag Berlin Heidelberg 2012 adverse effects.drug dev

摇晃

Elisabetta Straface,Lucrezia Gambardella,Marta Brandani,Walter Malorni

白杨

不断的变动

Flavia Franconi,Ilaria Campesi,Stefano Occhioni,Paola Antonini,Michael F. Murphy

宫殿般

Gerd Glaeske,Cornelia Gerdau-Heitmann,Friederike Höfel,Christel Schicktanz

尊重

APEX

DEMN

无脊椎

ATOPY

What a Difference an X or Y Makes: Sex Chromosomes, Gene Dose, and Epigenetics in Sexual Differentia effects of sex chromosome complement (XX vs. XY) and hormonal effects. Several lines of evidence implicate epigenetic processes in the control of sex differences, although a great deal of information is needed about sex differences in the epigenome.

培养

Considerations of Sex and Gender Differences in Preclinical and Clinical Trialspecific examples of drugs which have been withdrawn from the market because of side effects in women. Additional information related to sex and gender in preclinical testing, trial design, challenges to recruitment of women for clinical trials and statistical methods for analysis of data also is considered.