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Titlebook: Sex and Gender Differences in Pharmacology; Vera Regitz-Zagrosek Book 2012 Springer-Verlag Berlin Heidelberg 2012 adverse effects.drug dev

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Sex Differences in Drug Effects: Interaction with Sex Hormones in Adult Life often translated to women and their exact response to drugs is still not well known..The available evidence suggests that sex hormones influence drug absorption, distribution, metabolism, pharmacodynamics, and adverse effects. For instance, many cardiovascular drugs are metabolized by enzymes of th
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“Gender-Specific Drug Prescription in Germany” Results from Prescriptions Analysescy. In secondary prophylaxis after acute myocardial infarction, the characteristic prescription features of the various medicinal products that are used for both men and women (such as platelet aggregation inhibitors, beta-receptor blockers, ACE-inhibitors, statins) have become similar; women’s stil
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Gender and Polypharmacotherapy in the Elderly: A Clinical Challenge to differences in pharmacokinetics and - dynamics which make them more vulnerable to drug exposure. Thus, inappropriate prescribing contributes to hospitalization, poor quality of life, costs, compliance issues and poor outcomes. More preclinical and clinical studies with elderly patients and espec
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Sex and Gender Differences in Cardiovascular Drug Therapygs require a particularly careful dose adaptation in women: the beta-blocker metoprolol, the calcium channel blocker verapamil, loop-, and thiazide diuretics. In conclusion, sex differences in pharmacokinetics and pharmacodynamics have to be taken into account for cardiovascular drug therapy in wome
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Sex and Gender Aspects in Antiarrhythmic Therapyes in drug responses and metabolisms. Undoubtedly, determining the effect of gender on cardiac function will be difficult and require sophisticated methodologies. However, gender differences underlying predilection to distinct arrhythmia syndromes must be revealed so that new therapeutic strategies
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