| 书目名称 | Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin‘s Neuroendocrine Sys | | 编辑 | Andrzej T. Slominski,Michal A. Zmijewski,Jeffery D | | 视频video | | | 概述 | Includes supplementary material: | | 丛书名称 | Advances in Anatomy, Embryology and Cell Biology | | 图书封面 |  | | 描述 | .The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other physical and chemical agents. Examples of local biologically active products are cytokines, biogenic amines (catecholamines, histamine, serotonin and N-acetyl-serotonin), melatonin, acetylocholine, neuropeptides including pituitary (proopiomelanocortin-derived ACTH, b-endorphin or MSH peptides, thyroid stimulating hormone) and hypothalamic (corticotropin-releasing factor and related urocortins, thyroid-releasing hormone) hormones, as well as enkephalins and dynorphins, thyroid hormones, steroi | | 出版日期 | Book 2012 | | 关键词 | corticosteroids; corticotropin-releasing factor; melatonin; neuroendocrine functions; neuropeptides; sero | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-19683-6 | | isbn_softcover | 978-3-642-19682-9 | | isbn_ebook | 978-3-642-19683-6Series ISSN 0301-5556 Series E-ISSN 2192-7065 | | issn_series | 0301-5556 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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发表于 2025-3-21 16:18:45
