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Titlebook: Mechanisms and Consequences of Proton Transport; Tetsuro Urushidani,John G. Forte,George Sachs Book 2002 Springer Science+Business Media N

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Mutational Analysis of Gastric Proton Pump, α- and β-Subunitsains three conserved disulfide bonds and seven N-linked carbohydrate chains in the ectodomain. This subunit is also essential for the functional expression of the proton pump, and is involved in the structural and functional maturation as well as intracellular transport of the functional holoenzyme (.).
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Host-Specific , Inhibition of H,K-ATPase α Subunit Gene Expressionne glycoproteins and gly-colipids ensure bacterial adhesion in this relatively high pH zone. Most prominently, . takes up urea through proton-regulated mechanisms elegantly described by George Sachs (.); urease activity produces CO. and ammonia, neutralizing hydrogen ions in the immediate vicinity of the organism.
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Role of Cytokines in ,-Induced Gastric Epithelial Cell Matrix Metalloproteinase Secretion and Activausly shown that . infection of AGS cells increased secretion of epithelial MMPs-1 and -3 and bacterial MMP-3-like activity (.). Our aim in the present study was to characterize the relationship between activation of matrix metalloproteinases and IL-1β and TNFα, potent stimulators of IL-8 secretion in gastric epithelia during . infection.
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