Titlebook: Mechanisms and Consequences of Proton Transport; Tetsuro Urushidani,John G. Forte,George Sachs Book 2002 Springer Science+Business Media N

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The Gastric H/K ATPase in the Pathogenesis of Autoimmune Gastritisse of this disease. The gastritis results in loss of parietal cells that secrete intrinsic factor required for vitamin B12 absorption in the small intestine. The target antigen of these parietal cell antibodies is the gastric H/K ATPase responsible for secretion of HC1. To examine the role of the ga

congenial

Duodenal Protection: Influence of Melatonin and other Intestinal Transmitters on Duodenal Bicarbonataccepted as the most important defence mechanism against acid discharged from the stomach (4,6). HC0.. entering the continuous layer of visco-elastic mucus gel on top of the epithelial surface maintains pH in its cell-facing portion at neutrality at acidities encountered in the healthy duodenum.

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Ethanol Increases Intracellular Free Calcium, Closes Gap Junctions and Decreases Cell Volume in Primevels, the patency of gap junctions and cell volume changes in ethanol exposed gastric epithelial cell monolayers. Intracellular free calcium concentration was increased, gap junctions were closed and cell volume was decreased after exposure to 5% (vol/vol) ethanol. Since gap junctions are known to

HEPA-filter

homeostasis

decipher

Acid Induces Duodenal Epithelial Acidification and HC03 - Secretion via Activation of the Na+:HC03 -oses the duodenal mucosa to profound pH stress .. With the measurement of robust epithelial HC0.. secretion and neutral pH in the juxtamucosal mucus gel, despite the presence of luminal acid, the bicarbonate hypothesis was developed, wherein HC0.., secreted by the epithelial cells, completely neutra

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Insights Into the Cell Biology, Development and Pathology of the Gastric Mucosa Revealed in Gastric le for gastric luminal acidification (., ., .). The gastric H./K.-ATPase is composed of two non-covalently linked subunits, an α (H/Kα) and a β (H/Kβ), with apparent molecular weights of 95 kDa and 60–90 kDa, respectively (., .). H/Kα (encoded by the mouse gene . contains the catalytic sites of the

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