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Titlebook: Immunogenetics; Methods and Applicat Frank T. Christiansen,Brian D. Tait Book 2012 Springer Science+Business Media New York 2012 DNA sequen

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书目名称Immunogenetics
副标题Methods and Applicat
编辑Frank T. Christiansen,Brian D. Tait
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Immunogenetics; Methods and Applicat Frank T. Christiansen,Brian D. Tait Book 2012 Springer Science+Business Media New York 2012 DNA sequen
描述.The HLA molecules are important regulators of the immune response through mediating antigen presentation and interaction between key immune mediating cells. They are also the major histocompatibility barriers to transplantation, which is the clinical paradigm of the self versus non self concept. It is now recognized that this diverse range of gene systems involved in the control of the immune response have been shown to be important in many aspects of clinical practice. As a result many new molecular and cellular methods have been developed for identifying these genes and their polymorphisms, and immunogenetic laboratories specializing in these methods have developed to support transplantation and other clinical programs. .Immunogenetics: Methods and Applications in Clinical Practice .focuses on methods for human clinical practice. The emphasis rests on those assays which are of established or potential clinical utility and are likely to be included in the repertoire of tests provided by a routine diagnostic and service laboratory. This volume also contains several review chapters of the MHC complex, the KIR complex, the human immunoglobulin allotypes, as well as reviews of the me
出版日期Book 2012
关键词DNA sequencing; HLA molecules; HLA typing; Immunogenetic Data; Major Histocompatibility Complex (HMC)
版次1
doihttps://doi.org/10.1007/978-1-61779-842-9
isbn_softcover978-1-4939-5917-4
isbn_ebook978-1-61779-842-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media New York 2012
The information of publication is updating

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HLA Typing by SSO and SSP Methods,s are very useful for clinical and research purposes and can provide generic (low resolution) to allelic (high resolution) typing results. This chapter provides an overview of the SSO and SSP methods in relation to HLA typing.
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Simple Methods for the Detection of HLA-G Variants in Coding and Non-coding Regions,and easy feasible approaches are needed for the detection of HLA-G variants in coding and non-coding regions. Here we summarize a set of methods for the identification of variants in the exon 2–4, in the 3′ untranslated region and in the gene promoter region of the HLA-G gene.
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