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Titlebook: Genetic Epidemiology; Methods and Protocol Evangelos Evangelou Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018

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https://doi.org/10.1007/978-3-642-92786-7his chapter provides an overview of the methods used for meta-analysis of common and rare single variants and also for gene/region-based analyses; common variants are mainly identified via genome-wide association studies (GWAS) and rare variants through various types of sequencing experiments.
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Die mechanische Einrichtung des Mikroskopss challenges that are usually overlooked in traditional gene mapping. This chapter describes some of the most common challenges and opportunities to use human genetics to identify and validate novel drug targets.
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Meta-Analysis of Common and Rare Variants,his chapter provides an overview of the methods used for meta-analysis of common and rare single variants and also for gene/region-based analyses; common variants are mainly identified via genome-wide association studies (GWAS) and rare variants through various types of sequencing experiments.
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A Primer in Mendelian Randomization Methodology with a Focus on Utilizing Published Summary Associa methods and practical guidance for conducting an MR study using summary association data. We show that the analysis is straightforward utilizing either the MR-base platform or available packages in R. However, further research is required for the development of specialized methodology to assess MR assumptions.
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