Titlebook: Genetic Epidemiology; Methods and Protocol Evangelos Evangelou Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018

Pcos971

Genome-Wide Association Studies,e, common variant” theory, and will review how we finally afforded to capture the common variance in genome to make GWAS possible. Finally, we will go over technical aspects of GWAS such as genotype imputation, epidemiologic designs, analysis methods, and considerations such as genomic inflation, multiple testing, and replication.

prodrome

Das Methoden-Repertoire von Lehrerne applicable for family-based rare variant analysis. Here, I present three published statistical approaches for family-based rare variant analysis for: 1. continuous traits, 2. binary traits, and 3. multiple correlated traits.

匍匐

大猩猩

Novel Methods for Family-Based Genetic Studies,e applicable for family-based rare variant analysis. Here, I present three published statistical approaches for family-based rare variant analysis for: 1. continuous traits, 2. binary traits, and 3. multiple correlated traits.

Junction

From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS Results,evelop better preventive and curative strategies? Current efforts are shifting to focus on these questions as we move from identifying variants to understanding their effects. Here I provide a broad overview of the main technical concerns and current bottlenecks as we approach this new phase.

油毡

百灵鸟

绝缘

Negligible

Genome-Wide Association Studies,nome-wide association studies (GWAS). In this chapter, we review the key concepts that underlie the GWAS approach. We will describe the “common disease, common variant” theory, and will review how we finally afforded to capture the common variance in genome to make GWAS possible. Finally, we will go

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