Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Living reference work 20210th edition Gene carriers.Gene therapy.Antitumor.Gene editing.Cationic pol

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Molecular Strings Modified Gene Delivery System,. Polycationic gene carriers have attracted increasing attention due to non-immunogenicity, easy manufacture, and flexible properties. However, high transfection efficiency and low cytotoxicity is a dilemma in the design of polycationic gene carriers. In this chapter, a simple and versatile strategy

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Peptide-Modified Polycations with Acid-Triggered Lytic Activity for Efficient Gene Delivery,ucleic acid–based therapeutics, including plasmid DNA (pDNA), small interfering RNA (siRNA), messenger RNA (mRNA), micro-RNA (miRNA), and CRISPR/Cas, have entered different phases of clinical trials. However, in vivo delivery of this class of drugs has encountered various obstacles, especially endo/

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