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Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Living reference work 20210th edition Gene carriers.Gene therapy.Antitumor.Gene editing.Cationic pol

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发表于 2025-3-21 17:44:45 | 显示全部楼层 |阅读模式
书目名称Gene Delivery
编辑Huayu Tian,Xuesi Chen
视频video
概述Serves as an everyday reference for scientists, practitioners and students in gene delivery.Presents recent developments of nanoparticles for clinical gene therapy.Employs a systematic approach offeri
丛书名称Biomaterial Engineering
图书封面Titlebook: Gene Delivery;  Huayu Tian,Xuesi Chen Living reference work 20210th edition  Gene carriers.Gene therapy.Antitumor.Gene editing.Cationic pol
描述Gene therapy has been regarded as a great potential for specific treatment of gene-related human diseases, such as cancer, genetic and epidemic diseases. Gene therapy refers to the biomedical technology that inserts normal or therapeutic exogenous genes into target cells to repair or replace defective genes in target cells, so as to achieve the purpose of treating diseases. Efficient gene delivery systems are the crucial roles for successful implementation of gene therapy. This book provides a platform for young scholars and students to systematically understand the preparation and characterization of the existing non-viral gene delivery systems, as well as providing a technology platform for clinical gene therapy.
出版日期Living reference work 20210th edition
关键词Gene carriers; Gene therapy; Antitumor; Gene editing; Cationic polymers
doihttps://doi.org/10.1007/978-981-33-6198-0
isbn_ebook978-981-33-6198-0
issn_series 2523-8809
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发表于 2025-3-21 21:50:27 | 显示全部楼层
The Entire Guard Followed Pravyk,lar strategy to drive the assembly of peptide dendrimers and polypeptides into capsid-like nanoparticles (CLNs) for gene delivery. Low-generation poly(L-lysine) dendrimers and glutamic acid-functionalized polypeptides can assemble into dendritic supramolecular amphiphiles via supramolecular interact
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https://doi.org/10.1007/978-1-4613-9311-5owever, delivering the considerable concentration of right molecule to the desired cells or tissues and overcome multidrug resistance (MDR) are challenging tasks in gene therapy. To date, several viral and nonviral vectors for gene delivery systems have been developed and possess some serious unreso
发表于 2025-3-22 10:32:29 | 显示全部楼层
Radiation Dose and Imaging Protocols,py. Therapeutic gene was condensed by polycation polyethylenimine (PEI) and polyanion poly-.-glutamate (PLG), further in situ tightened by aldehyde-modified polyethylene glycol (PEG) via Schiff-base reaction. The Schiff-base bonds were stable in neutral physiological pH but cleavable in acidic tumor
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Chest Pain with Normal Coronary Arterieses and cationic polymers are unstable because of their weak electrostatic interactions, resulting in polymer/nucleic acid polyplexes with poor serum resistance and a short circulation time in vivo. Furthermore, most polymer/nucleic acid polyplexes mixture exhibit high toxicity because an excess of h
发表于 2025-3-23 02:39:39 | 显示全部楼层
Sonja Beckh,Gebhard Mathis,Christian Görgities. In this section, we demonstrated a molecular and supramolecular approach of arginine-rich nanohybrids (ARNHs) based on coassembly of low-generation dendrimers and inorganic nanoparticles for visible gene delivery. Arginine-rich corona of ARNHs provided efficient DNA-binding ability, high inte
发表于 2025-3-23 07:31:04 | 显示全部楼层
Giovanni Volpicelli,Luna Gargani. Polycationic gene carriers have attracted increasing attention due to non-immunogenicity, easy manufacture, and flexible properties. However, high transfection efficiency and low cytotoxicity is a dilemma in the design of polycationic gene carriers. In this chapter, a simple and versatile strategy
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