Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Living reference work 20210th edition Gene carriers.Gene therapy.Antitumor.Gene editing.Cationic pol

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Molecular and Supramolecular Construction of Arginine-Rich Nanohybrids for Visible Gene Delivery, gene delivery and monitor protein expression. In vitro and in vivo results demonstrated that the ARNHs exhibited high gene transfection efficiency, good biocompatibility, facile fabrication, and real-time bioimaging capabilities.

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Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA, internalized siRNA. We elaborately described the synthesis of the polymer, preparation, and characterization of the siRNA-loaded nanoparticles, the process of internalization and intracellular trafficking of nanoparticles, as well as . and . gene silencing and cancer treatment effects of proposed organic nanoformulation.

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Bioreducible Zinc (II)-Coordinative Polyethylenimine with Low Molecular Weight for Robust Gene Delilogues, which can be cleaved by abundant glutathione in cytoplasm. The Zn coordination strategy dramatically enhances transfection efficacy of LMW cationic polymers across diverse cell types, including primary and stem cells.

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Living reference work 20210th editionementation of gene therapy. This book provides a platform for young scholars and students to systematically understand the preparation and characterization of the existing non-viral gene delivery systems, as well as providing a technology platform for clinical gene therapy.

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A Codelivery System of Anticancer Drug Doxorubicin and Tumor-Suppressor Gene p53 Based on Polyphosponic carrier can be respectively prepared through a combination of ring-opening polymerization (ROP) and “click” reaction. First, poly(ethylene glycol)monomethyl ether (mPEG) is used to initiate the ring-opening polymerization of a cyclic phosphoester monomer, 2-(but-3-yn-1-yloxy)-2-oxo-1,3,2-dioxap

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Bioreducible Zinc (II)-Coordinative Polyethylenimine with Low Molecular Weight for Robust Gene Delitocol describes a zinc(II) coordinative strategy to transform common LMW cationic polymers to highly efficient and safe gene vehicles. LMW cationic polymers exhibit lower efficacy compared to their high molecular weight counterparts, largely attributed to weaker nucleic acid binding. From this point