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Titlebook: Gastric Cytoprotection; A Clinician’s Guide Daniel Hollander,Andrzej S. Tarnawski Book 1989 Springer Science+Business Media New York 1989 a

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Acid Hypersecretion Important Factor or Innocent Bystander?to gastric secretions. This feature, together with the demonstration that gastric juice has the capacity to destroy animal tissues, has resulted in the belief that peptic ulceration is, in some way, caused by exposure of the affected mucosa to gastric secretions.
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Book 1989enomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse­ quently, over the past 150 years, we have m
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Eric D. Spitzer,George S. Kobayashic mucosa in this region gradually (through the intermediate zone) converts into an antral type with mucoid glands containing mucus and endocrine cells, especially gastrin-produc-ing G cells. The pylorus is the sphincteric orifice opening into the duodenum.
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https://doi.org/10.1007/978-3-319-61771-8rom our laboratory have raised the possibility that specific dietary factors can be extremely effective in preventing mucosal injury by alcohol, aspirin, and perhaps other irritants. These protective dietary factors are the two essential fatty acids — arachidonic and linoleic and related fatty acids.
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Pathomorphology of Gastric Mucosal Injuryc mucosa in this region gradually (through the intermediate zone) converts into an antral type with mucoid glands containing mucus and endocrine cells, especially gastrin-produc-ing G cells. The pylorus is the sphincteric orifice opening into the duodenum.
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The Role of Nutrient Essential Fatty Acids in Gastric Mucosal Protectionrom our laboratory have raised the possibility that specific dietary factors can be extremely effective in preventing mucosal injury by alcohol, aspirin, and perhaps other irritants. These protective dietary factors are the two essential fatty acids — arachidonic and linoleic and related fatty acids.
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https://doi.org/10.1007/978-90-481-2408-4, led to the administration of strongly antisecretory doses with only minimal side effects and accelerated the healing of peptic ulcer. More recently, omeprazole, a substituted benzimidazole that inhibits (H.-K.)-ATPase within the parietal cell canaliculi, was shown to inhibit acid secretion totally and to induce duodenal ulcer healing in 2 weeks.
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