| 书目名称 | Gastric Cytoprotection | | 副标题 | A Clinician’s Guide | | 编辑 | Daniel Hollander,Andrzej S. Tarnawski | | 视频video | | | 图书封面 |  | | 描述 | Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal muco | | 出版日期 | Book 1989 | | 关键词 | attention; cell; gastrointestinal tract; muscle; pathogenesis; pathophysiology; physiology; production; regu | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-5697-4 | | isbn_softcover | 978-1-4684-5699-8 | | isbn_ebook | 978-1-4684-5697-4 | | copyright | Springer Science+Business Media New York 1989 |
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发表于 2025-3-21 18:46:57
