Titlebook: Gastric Cytoprotection; A Clinician’s Guide Daniel Hollander,Andrzej S. Tarnawski Book 1989 Springer Science+Business Media New York 1989 a

钢笔尖

Lucio Luciani (Head),Francesco Piscioliunds are biologically active, affect most cellular functions, and have both physiologic and pharmacologic effects in animals and in humans. Prostaglandins (PG) represent one of two known groups of arachidonic acid metabolites, collectively known as eicosanoids (Fig. 1). Because of their gastric acid

Longitude

Palter

objection

B-cell

Epithelial Cell Renewalghout the GI tract because it maintains the functional integrity of the epithelium and is also necessary for the repair of mucosal injury. Thus, it is reasonable to expect that certain conditions and agents that predispose to peptic ulcer disease or mucosal injury may do so in part by affecting epithelial renewal in the upper GI tract.

Intact

978-1-4684-5699-8Springer Science+Business Media New York 1989

善辩

Book 1989ecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas­ troduodenal muco

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cid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas­ troduodenal muco978-1-4684-5699-8978-1-4684-5697-4

Genistein

achlorhydria

Gastric Blood Flow and Mucosal Defenseortant components of the gastric defensive system are covered in substantial depth in other chapters of this volume. For this reason, only very brief mention of these other important defensive factors will be made here.