Titlebook: G-Quadruplex Nucleic Acids; Methods and Protocol Danzhou Yang,Clement Lin Book 2019 Springer Science+Business Media, LLC, part of Springer

mercenary

Flatter

Chromatin Immunoprecipitation Assay to Analyze the Effect of G-Quadruplex Interactive Agents on these studies also provide strong evidence that G-quadruplex structures are stabilized by binding to small molecules, resulting in the modulation of the transcription of genes whose promoters form G-quadruplexes. Here, we describe a chromatin immunoprecipitation (ChIP) assay to determine whether G-quad

一瞥

FADE

Innocence

Single-Molecule Investigations of G-Quadruplex,ion kinetics of the structures. Although the core structural element in a G-quadruplex is simple and requires only four tandem repeats of Guanine rich sequences, there is rather rich conformational diversity in this structure. Corresponding to this structural diversity, it displays involved transiti

Crayon

东西

G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy,rming sequences exist throughout the genome and G4 structures are shown to be involved in many processes including DNA replication and gene expression. The single-molecule total internal reflection fluorescence (TIRF) microscopy has been employed to study G4 structure formation and protein binding i

Debate

浮雕宝石

针叶