Titlebook: G-Quadruplex Nucleic Acids; Methods and Protocol Danzhou Yang,Clement Lin Book 2019 Springer Science+Business Media, LLC, part of Springer

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35th Hemophilia Symposium Hamburg 2004Q)- and counterpart i-motif-forming sequences in the DNA nanostructure. Sequential manipulation of DNA strands in the DNA frame was performed to prepare a topologically controlled GQ/i-motif dsDNA. Using the strand displacement and the addition and removal of K., the topologically controlled GQ/i-mo

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https://doi.org/10.1007/978-90-313-8424-2rming sequences exist throughout the genome and G4 structures are shown to be involved in many processes including DNA replication and gene expression. The single-molecule total internal reflection fluorescence (TIRF) microscopy has been employed to study G4 structure formation and protein binding i

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,Sicht I: Die Weit-Sicht des Visionärs,cceptor molecule when the donor and acceptor are in close proximity to each other. Depending on the assay design, FRET can provide a real-time measurement of structural integrity and dynamics of biomacromolecules in solution and is particularly suitable for studying G-quadruplex (G4) nucleic acids a

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A. Calatzis,W. Schramm,M. SpannaglAnalytical ultracentrifugation is a powerful biophysical tool that provides information about G-quadruplex structure, stability, and binding reactivity. This chapter provides a simplified explanation of the method, along with examples of how it can be used to characterize G4 formation and to monitor small-molecule binding.

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易弯曲

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G-Quadruplex Nucleic Acids978-1-4939-9666-7Series ISSN 1064-3745 Series E-ISSN 1940-6029

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Quantitative Analysis of Stall of Replicating DNA Polymerase by G-Quadruplex Formation,he human genome exhibit G4-forming potential, the stability and topology of the G4s formed vary depending on the molecular environment. Here, we describe a protocol to quantitatively analyze the inhibitory effects of G4s with different stabilities and topologies on replication in conditions of molecular crowding.