Titlebook: Epigenetics of Aging; Trygve O. Tollefsbol Book 2010 Springer-Verlag New York 2010 Chromosom.DNA.Telomere.aging.genetics.senescence

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Volksstruktur und sozialer Gedankem the early development through the entire life span of an individual. This evolutionarily well–conserved group of proteins create and maintain epigenetic chromatin marks that are translated into means of maintaining a temporally and spatially regulated gene expression status. Among the many differe

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Panther

Amerikanische und deutsche Großdampfkesselmerous incremental programmatic shifts to dysfunctional states. Most current therapeutic treatments address illnesses characterizing the elderly symptomatically, largely attempting to reduce the severity of the disease rather than delaying or preventing its occurrence; this retrospective strategy is

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Willi Paul Adams,Erich Angermannstone modification, are determinants of normal development and can change during aging. Some of the epigenetic alterations described during aging, as hypermethylation at specific promoters and decrease of global DNA methylation, are also associated with tumour development. The epigenetic changes occ

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Amerikastudien / American Studiesg the expression of genes involved in memory processes. In fear conditioned mice, CpG islands in the promoter regions of the memory-linked genes, . and ., undergo either hypomethylation . or hypermethylation .. By altering the expression of these genes, epigenetic mechanisms can affect the ability t

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乐章

https://doi.org/10.1007/978-3-322-96216-4 telomere function. How both aspects are connected and how they impact on organismal fitness will be the subject of intense research in the coming years. This chapter reviews different aspects of telomere biology and discusses their implications in the aging process.