Titlebook: Epigenetics of Aging; Trygve O. Tollefsbol Book 2010 Springer-Verlag New York 2010 Chromosom.DNA.Telomere.aging.genetics.senescence

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Role of Epigenetics in Age-Related Long-Term Memory Lossry loss is best seen by studying the classic age-related disease, Alzheimer’s disease (AD), which is characterized by severe memory loss. Biological aging correlates with a loss of expression and activity of certain epigenetic modulating enzymes, such as DNA methyltransferase1. The loss of maintenan

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many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an imp978-1-4899-8310-7978-1-4419-0639-7

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