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Titlebook: Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3; Kenneth V. Honn,Lawrence J. Marnett,Patrick Y.-K.

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Rucong Yu,Tianjun Zhou,Guangqing Zhouhas demonstrated the occurrence of two isoforms of 12-lipoxygenase (platelet-type and leukocyte-type) which were distinguished in terms of substrate specificity, the cross-reactivity of their antibodies and the homology of their amino acid sequences.. The leukocyte-type 12-lipoxy-genases have been d
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Development and Implementation of Ship BWMSts occurrence correlates to the presence and the amount of subarachnoid clot. It is different from ordinary constriction of vessel, since the cerebral vasospasm is delayed onset and long lasting contraction of the vessel which also involves histological changes. Although almost all substances which
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https://doi.org/10.1007/978-94-017-1237-8nd lipoproteins (Belkner et al., 1993). The enzyme is expressed in high yield in rabbit reticulocytes, in human airway epithelial cells and eosinophils and in smaller amounts in other mammalian cells (for review see Ford-Hutchinson, 1991a). In contrast to the 5-lipoxygenase which is involved in the
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Mark W. Barnett,Ruth F. Watson,Peter C. Kindly regulate cell growth. To date, a number of tumor suppressor genes (e. g., RB, p53, DCC, APC/MCC, NF1, NF2, WT1, VHL, BRCA1, MST1, and WAF1/CIP1 genes) have been identified and have been shown to be important in a variety of human malignancies such as cancers of the colon, lung, breast, and esopha
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Wendelyn H. Inman,Graham Carpenters, endothelial cells, etc.) in addition to tumor cell interactions with the extracellular matrix. These interactions are mediated by a variety of cell surface receptors including cadherins, CAMs, selectins, and integrins.. To date a number of integrin receptors have been shown to be critically invol
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W. Hoffmann,A. Königstorfer,S. Sterrertors (1). One of these genes encodes the inducible form of prostaglandin synthase (2), now known as PGS-2 or cyclooxygenase 2 (COX-2). We demonstrated that the product of the PGS-2 gene has both cyclooxygenase and hydroperoxidase activities (3); that PGS-2 is a functional prostaglandin synthase. At
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Werner A. Mueller,Monika Hassel,Maura Grealymmatory stimuli. are about 63% identical in their primary amino acid sequence and >90% of the putative “active site” amino acids are conserved.. Despite this similarity, recent studies have shown that these enzymes are pharmacologically distinct.. Similarly, COX-1 and COX-2 from different species sh
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