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Titlebook: Early Life Origins of Ageing and Longevity; Alexander Vaiserman Book 2019 Springer Nature Switzerland AG 2019 Developmental programming.Ag

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https://doi.org/10.1007/978-3-642-96198-4Multigeneration Study to address this issue. Mortality in G1 (N = 9,565) was followed 1961–2015 and analysed by their parents’ (G0) age-at-death using Cox regression. For an almost entirely deceased segment of G1 (n = 1,149), born 1915–1917, we compared exact age-at-death with G0 parents’ age-at-dea
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https://doi.org/10.1007/978-94-017-3728-9le of epigenetic mechanisms in mediating these life-long effects, including DNA methylation histone modification and regulation by non-coding RNAs, has been demonstrated. Early-life environmental conditions were repeatedly shown to significantly affect life-course change of epigenetic patterns known
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https://doi.org/10.1007/978-3-030-24958-8Developmental programming; Aging; Age-related disease; Longevity; Epigenetics; biogerontology; gene expres
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978-3-030-24960-1Springer Nature Switzerland AG 2019
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Book 2019itionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life. .While other books in the field concentrate on the develop
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