Titlebook: Early Life Origins of Ageing and Longevity; Alexander Vaiserman Book 2019 Springer Nature Switzerland AG 2019 Developmental programming.Ag

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l regenerative potential mediate healthy aging at the cellular level. This chapter is an overview of fundamental biological platforms for developmental programming of life-course cell level dynamics involved in building the fetal body.

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https://doi.org/10.1057/9780230390218al corticosteroids and intrauterine growth restriction (IUGR), pups are born with low birth weights and develop type 2 diabetes (T2D) as adults. In the IUGR model, development of T2D is dependent on interleukin 4 in the neonatal period. Development of the fetal immune system has the potential to eff

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Zeitschriften und Medienunterhaltungsk of poor adult cardiovascular and metabolic health. However, in contemporary Western societies, maternal over-nutrition, overweight and obesity are far more common nutritional issues and this has led to an increased focus of the field on the long-term consequences of exposure to these stimuli in e

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Zeitstrategien in Innovationsprozessenrly life adversity. These neurons regulate cognitive-emotional states, notably impulsivity, and reward-based decision-making, thus defining psychiatric phenotypes and contributing to intensify behaviors that in turn promote metabolic disturbances. We will also apply the concept of differential susce

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https://doi.org/10.1007/978-3-642-96198-4hters compared to mothers. Parents’ and maternal grandmother’s longevity were associated with resilience in subsequent generations. Resilience scores of G2 men were also associated with those of their G3 sons and with their own mortality in midlife. We conclude that chances of reaching a high age ar