Titlebook: DNA Topoisomerase Protocols; Volume II: Enzymolog Neil Osheroff,Mary-Ann Bjornsti Book 2001 Humana Press 2001

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Habiba Drias,Farouk Yalaoui,Allel Hadjali among the topoisomerases in promoting negative supercoiling of DNA (.,.). A variety of studies have shown that gyrase is essential for bacterial growth with roles in DNA replication, transcription, and recombination. Moreover, in combination with the relaxing activity of DNA topoisomerase I, gyrase

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https://doi.org/10.1007/978-3-031-14489-9ic functions (.–.). ATP binding is necessary to close the protein clamp (.,.) and trigger DNA strand passage (.,.), whereas hydrolysis is necessary for topoisomerase II recycling (.,.). Beyond the the critical roles played by ATP in the catalytic cycle of the enzyme, interactions between type II top

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Paraconsistent Rough Set Algebras one DNA strand and allows the passage of single-stranded DNA through the generated nick, whereas topoisomerase II introduces a transient double-stranded break and permits passage of another double helix through the gap (.–.). Owing to the physiological importance of the topoisomerase-mediated cleav