| 书目名称 | Co-signal Molecules in T Cell Activation |
| 副标题 | Immune Regulation in |
| 编辑 | Miyuki Azuma,Hideo Yagita |
| 视频video | |
| 概述 | Explains the basic concepts and roles of co-signal molecules.Discusses applied and clinical studies using co-stimulation mechanisms.Presents a variety of potential therapeutic applications |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated..Co-signal Molecules in T Cell Activation .will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science. . |
| 出版日期 | Book 2019 |
| 关键词 | Costimulation; Coinhibition; Immune Regulation; CD28; TNF-TNFR; T lymphocytes; Cancer Immunotherapy |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-32-9717-3 |
| isbn_softcover | 978-981-32-9719-7 |
| isbn_ebook | 978-981-32-9717-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer Nature Singapore Pte Ltd. 2019 |
发表于 2025-3-21 19:49:35
