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Titlebook: Clinical Trials in Neurology; Roberto J. Guiloff (Consultant Neurologist) Book 2001 Springer-Verlag London 2001 Ethical Issues.Parkinson.c

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书目名称Clinical Trials in Neurology
编辑Roberto J. Guiloff (Consultant Neurologist)
视频video
概述Drug companies rely on trials to show the efficacy or problems relating to new drugs.This new multi-contributor book aims to improve the efficacy of neurological trials by improving trial design
图书封面Titlebook: Clinical Trials in Neurology;  Roberto J. Guiloff (Consultant Neurologist) Book 2001 Springer-Verlag London 2001 Ethical Issues.Parkinson.c
描述.Clinical Trials in Neurology. comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
出版日期Book 2001
关键词Ethical Issues; Parkinson; clinical research; clinical trial; dementia; drug; drug development; ethical and
版次1
doihttps://doi.org/10.1007/978-1-4471-3787-0
isbn_softcover978-1-84996-856-0
isbn_ebook978-1-4471-3787-0
copyrightSpringer-Verlag London 2001
The information of publication is updating

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Drug Regulatory Requirements in the United Statesr-state commerce) unless it is the subject of an approved New Drug Application (NDA). The requirement for an NDA is the linchpin of the federal system of pre-market clearance of new drug products that operates within the United States.
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Analysis of Results: Statistical Principlesled clinical trial, even an effective treatment accounts for only a small portion of the resulting range and variability of clinical measurements. In other words, there is usually a lot of “noise” in the data. Ultimately, a mass of data must be condensed into quantities (statistics) which can be use
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The Intention-to-Treat Principle for Clinical Trialsization that distinguishes the controlled clinical trial from other forms of medical research. During the 1920s, R. A. Fisher developed the concept of randomization as a method of assigning “treatments” to blocks or plots of land in agricultural experiments [2]. Sir Austin Bradford Hill, considered
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