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Titlebook: Clinical Trials in Neurology; Roberto J. Guiloff (Consultant Neurologist) Book 2001 Springer-Verlag London 2001 Ethical Issues.Parkinson.c

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César García-Díaz,Arjen van Witteloostuijnand the data are accurate and credible. Guidance for quality control procedures and data monitoring for clinical trials has evolved through the development of Good Clinical Practice (GCP) standards. There are many GCP guidelines used in the world, which has resulted in many different standards of GC
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Fidel Aznar,Mar Pujol,Ramón Rizotherefore, that the reader already has considerable familiarity with descriptive and inferential statistics and, in addition to knowing about means, medians, variances and standard deviations, has encountered the general framework of hypothesis tests, confidence intervals and so forth and particular
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Oscar Luaces ,José A. Gámez,Emilio Corchadoled clinical trial, even an effective treatment accounts for only a small portion of the resulting range and variability of clinical measurements. In other words, there is usually a lot of “noise” in the data. Ultimately, a mass of data must be condensed into quantities (statistics) which can be use
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Fidel Aznar,Mar Pujol,Ramón Rizotime intervals start at a starting time (or starting point), and end at an end time (or end point). In a clinical trial, the starting time is usually the date on which a patient joined the trial. The end time is typically the death date of the patient or the end date of the trial, whichever is soone
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Advances in Artificial Intelligenceization that distinguishes the controlled clinical trial from other forms of medical research. During the 1920s, R. A. Fisher developed the concept of randomization as a method of assigning “treatments” to blocks or plots of land in agricultural experiments [2]. Sir Austin Bradford Hill, considered
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Advances in Artificial Intelligencengly acknowledged by health care professionals, researchers and policy makers. Faced with unmanageable amounts of information, these groups require reliable summaries of research on which to base clinical and policy decisions [1] and to guide future research.
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Lecture Notes in Computer Scienceal clinical scales and functional scales) in evaluating treatments for dementia, most especially Alzheimer’s disease (AD), with emphasis on neuropsychological assessment in trials of drugs designed to treat cognitive symptoms. We begin with a brief overview of issues in the diagnosis of dementia. We
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