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Titlebook: Clinical Experiences with Budipine in Parkinson Therapy; Franz Gerstenbrand,Werner Poewe,Gerald Stern Conference proceedings 1985 Springer

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Wei Zhang,Duoqian Miao,Can Gao,Xiaodong Yuecused on achieving increased activation of striatal dopaminergic receptors. Initially, this end was accomplished by administering the precursor of dopamine, levodopa; certain unwanted effects of this amino acid, notably nausea and vomiting, were alleviated by concomitant administration of drugs, (ca
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Junxia Niu,Hong Zhao,William Zhuasy to define akinesia clearly and strictly, especially when its generating mechanism is discussed (Barbeau 1971; Hornykiewicz 1972). In this paper I would like to propose at least three different subgroups of akinesia in the clinical sense, considering their physiological and pharmacological mechan
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Leijun Li,Qinghua Hu,Xiangqian Wu,Daren Yuural mechanisms. There are reasons to question this opinion. Parkinsonian patients, adequately treated with L-dopa compounds and with an acceptable therapeutic response with respect to tremor, rigidity and akinesia, often report no improvement, or, as time passes, even deterioration of one or more o
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Rough Sets and Knowledge Technologyredressed in several ways: by administering anticholinergics to reduce the cholinergic surplus, by substituting for the lack of transmitter by giving levodopa, by direct stimulation of dopaminergic receptors, or by inhibition of dopamine reuptake. Whether a pharmacotherapeutic measure is successful
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