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Titlebook: Chemical Biology of Nucleic Acids; Fundamentals and Cli Volker A. Erdmann,Wojciech T. Markiewicz,Jan Barci Book 2014 Springer-Verlag Berlin

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978-3-662-51324-8Springer-Verlag Berlin Heidelberg 2014
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RNA as Major Components in Chemical Evolvable Systems,cal dynamic off-equilibrium systems. The bilayer surface of lipidic vesicles served for the anchoring and enrichment of macromolecules that could grow in size would interact with one another one thousand fold more frequently than unbound in solution and could sooner or later be internalised into the
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Effects of Ionic Liquid and Liposomes on the Structure, Stability, and Function of Nucleic Acids,eported. Little is known, however, about the behaviors of nucleic acids in heterogeneous conditions such as in the presence of liposomes and ionic liquids (ILs). In this chapter, I discuss the effects of liposome and ionic liquid on the structure, stability, and function of nucleic acids. A novel DN
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Oxidative Damage on RNA Nucleobases,xidative stress and its influence on nucleic acids are reported. In contrast to DNA oxidative lesions of RNA have been scarcely described in the literature so far. These known stable RNA base modifications which arise under oxidative stress are reviewed here with regard to their biophysical properti
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Use of FRET to Study Dynamics of DNA Replication,s must be regulated in order to control this process. Cellular integrity depends on the correct incorporation of each nucleotide and incorrectly incorporated bases must be removed by proofreading to prevent mutations. Lagging strand DNA polymerases and processivity clamps must be continuously recycl
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Design, Characterization, and Application of Imidazopyridopyrimidine:Naphthyridine Base-Pairing Motdazo[5′,4′:4,5]pyrido[2,3-.]pyrimidine (.) nucleosides and evaluated their base-pairing ability when incorporated into DNA duplexes. All possible .:. pairs thermally destabilized the duplexes, although the pair formed four hydrogen bonds between . units. On the other hand, the resulting duplexes wer
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