书目名称 | Chemical Biology of Nucleic Acids |
副标题 | Fundamentals and Cli |
编辑 | Volker A. Erdmann,Wojciech T. Markiewicz,Jan Barci |
视频video | http://file.papertrans.cn/225/224286/224286.mp4 |
概述 | Detailed and comprehensive overview of the various different RNA species.Bench to bedside approach.Written by leading authorities in the field.Includes supplementary material: |
丛书名称 | RNA Technologies |
图书封面 |  |
描述 | .This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future research.. |
出版日期 | Book 2014 |
关键词 | From bench to bed; Molecular basis of disease; Molecular medicine; Non coding RNA; RNA silencing; Therape |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-54452-1 |
isbn_softcover | 978-3-662-51324-8 |
isbn_ebook | 978-3-642-54452-1Series ISSN 2197-9731 Series E-ISSN 2197-9758 |
issn_series | 2197-9731 |
copyright | Springer-Verlag Berlin Heidelberg 2014 |