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Titlebook: Chemical Biology of Nucleic Acids; Fundamentals and Cli Volker A. Erdmann,Wojciech T. Markiewicz,Jan Barci Book 2014 Springer-Verlag Berlin

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Dependency Properties and Routed Events,oding system is thought to be the simplest among all extant living systems and to have originated by retrogression from the universal decoding system, induced mainly by genome economisation and directional mutation pressure during mitochondrial evolution. Thus, it is reasonable to speculate that the
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https://doi.org/10.1007/978-1-4302-2980-3xidative stress and its influence on nucleic acids are reported. In contrast to DNA oxidative lesions of RNA have been scarcely described in the literature so far. These known stable RNA base modifications which arise under oxidative stress are reviewed here with regard to their biophysical properti
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Brushes, Transforms, and Bitmaps,s must be regulated in order to control this process. Cellular integrity depends on the correct incorporation of each nucleotide and incorrectly incorporated bases must be removed by proofreading to prevent mutations. Lagging strand DNA polymerases and processivity clamps must be continuously recycl
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Brushes, Transforms, and Bitmaps,leoside scaffold that has only recently garnered attention involves imparting flexibility to the nucleobase instead of the sugar moiety. This flexibility can be achieved by splitting the purine base into its respective imidazole and pyrimidine components or by increasing the number of aromatic rings
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Brushes, Transforms, and Bitmaps,ryo-electron microscopy, focus on obtaining snapshots of the most stable conformer in the free-energy landscape. It is, however, imperative to fathom the conformations of other occupants of energy landscape as well that are transient in existence but are often the functionally active structures. NMR
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