Titlebook: Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease; A. Martin Municio,M. Teresa Miras-Portugal

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List of symbols and abbreviations,l signals such as light, odorants and chemical messengers between neighboring or distant cells. The interaction of these factors with specific receptors at the cell surface constitutes the first step in a cascade of biochemical events that underlies transmembrane signaling.

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conformity

List of symbols and abbreviations,diated hydrolysis of phosphatidylcholine (PC) has been demonstrated in our and other laboratories to be activated in response to growth factors and oncogenes (1,2). In this regard, we have also produced evidence that activation of PLC-catalyzed hydrolysis of phosphatidylcholine (PC-PLC) is an import

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List of symbols and abbreviations,expression of the inducible form of nitric oxide synthase in primary cultures of peritoneal macrophages and hepatocytes. The induction process is clearly observed after short (hours) incubation periods with phorbol esters, and is antagonized by endotoxins and some cytokines, recognized by their abil

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List of symbols and abbreviations,locus of PKC action is at the K.-channels controlling the duration or frequency of the action potentials; for this reason, the facilitation of glutamate release is observed only in synaptosomes under the repetitive depolarizations induced by the K.-channel blocker 4-aminopyridine, (4-AP), but not by

CAMP

Pb element, bulk, under pressure,these enzymes, the identification of physiologically important substrates has received a peculiar attention during the last decade. The myristoylated alanine-rich C kinase substrate (MARCKS) is a widely distributed . and . substrate that has been often used as a marker of the activation of the kinas

exostosis

List of symbols and abbreviations,llowing cascade of events: filtered HCO.- binds a H. to give H.CO.. Proton issued from hydration of cellular CO. is secreted into the tubular fluid (mainly via the apical Na/H antiporter) and combines to filtered HCO.- to give H.CO.. H.CO. is converted into CO. and H.O as rapidly as it is formed, be

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Pb element, bulk, under pressure, at concentrations down to the picomolar range in a wide variety of cells and tissues (for a review see Braquet et al., 1987). A role for PAF in the nervous system has been suggested by the ability of seizures (Kumar et al., 1988) and certain neurotransmitters (Bussolino et al., 1986; Sogos et al.,