Titlebook: Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease; A. Martin Municio,M. Teresa Miras-Portugal

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Biochemical and Immunological Characterization of Protein Kinase C Isozymes in Rat Kidney Proximal AII receptors were coupled to the inositol phosphate-Ca. signaling pathway (Poggioli et al., 1992) and to well known cAMP pathway (Woodcock and Johnson 1982). Thus, our results indicated that AII was able to activate the Ca.-phospholipid -dependent protein kinase C (PKC, Nishizuka, 1988). Both funct

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Phospholipid Degradation, Second Messengers and Activation of Cell Signaling Genes,ort-lived second messengers. The study of the signal transduction events that control PAF synthesis is only now beginning to evolve. However, two new clues about the biological activity of PAF in the brain have been found. In presynaptic nerve terminals, PAF enhances excitatory neurotransmitter rele

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NMDA Receptor-Stimulated Release of Arachidonic Acid: Mechanisms for the Bazan Effect,ges in membrane permeability by regulating ion channels (Keyser and Alger, 1990). PAF is proaggregatory and hemostatic; it may cause adhesion and activation of leukocytes and hence produce an inflammatory reaction at the blood-endothelial cell interface and open Ca. channels on presynaptic sites, ca

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Diadenosine Polyphosphates from Neuro-Secretory Granules: The Search for Receptors, Signals and Funesting the presence of a new receptor subtype in rat brain synaptic terminals, designated as P.- The diadenosine polyphosphate receptors in neurochromaffin cells and vascular endothelial cells from adrenal medulla are coupled to Ca. release from internal stores and stimulation of Protein Kinase C. T

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List of symbols and abbreviations,l signals such as light, odorants and chemical messengers between neighboring or distant cells. The interaction of these factors with specific receptors at the cell surface constitutes the first step in a cascade of biochemical events that underlies transmembrane signaling.

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BaTiO3 (hexagonal) [F] Tables, 1A-10,of IL-2 with specific high affinity receptors (IL-2R) expressed on T cells upon activation induces T cell proliferation. However, the molecular bases of IL-2 induced signal transduction mechanism are poorly understood.

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