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Titlebook: Cardiovascular Biology of Purines; Geoffrey Burnstock,James G. Dobson,Joel Linden Book 1998 Springer Science+Business Media New York 1998

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Recent Advances in Cardiac Adenosine Metabolism,cellular adenosine concentration is normally very low and adenosine is continuously formed extracellularly from released adenine nucleotides, the concentration gradient for adenosine in the normoxic heart is from extracellular to intracellular. This gradient is rapidly reversed during hypoxia or pharmacological inhibition of adenosine kinase.
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Roles of Adenosine in Angiogenesis,ch as nitric oxide and vascular endothelial growth factor. Through the interplay of tissue oxygen tension, adenosine, nitric oxide and vascular endothelial growth factor, a complex physiological control system ensures the matching of vascularity and metabolic needs in a variety of organs and circumstances.
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Nuclear Energy and International Cooperationnd it may be mitochondrial. If this is the case, it will be imperative to determine the mechanism by which opening of these channels can exert cardioprotective and energy sparing effects. Determination of these mechanisms may potentially lead to the development of novel and efficacious therapeutics.
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Nuclear Export of Herpes Virus RNA,recombinant receptors specific for ATP divided in two families cf ionotropic ligand-gated ion channels P2X-purinoceptors and metabotropic G protein-coupled P2Y-purinoceptors. Molecular characterization and localization of several P2-purinoceptor subtypes in the heart provide functional evidence in f
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