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Titlebook: Systems Biology of RNA Binding Proteins; Gene W. Yeo Book 2014 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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RNA-Binding Protein Misregulation in Microsatellite Expansion Disorders,is of these disorders has already uncovered novel pathogenic mechanisms, including RNA toxicity and repeat-associated non-ATG (RAN) translation, and current studies suggest that additional surprising insights into cellular regulatory pathways will emerge in the future.
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RNA-Binding Proteins in Heart Development, cause cardiomyopathy in humans and animal models. Here we review the complexity of late heart development and the current information regarding how RBPs control aspects of postnatal heart development. We also review how activities of RBPs are modulated adding complexity to the regulation of develop
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Splicing Code Modeling, The inferred regulatory models can then be applied to genomic sequences or experimental conditions that have not been measured to predict splicing outcome. Moreover, the models themselves can be interrogated to identify new regulatory mechanisms, which can be subsequently tested experimentally. In
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Book 2014affecting 3’ end formation, controlling RNA stability and regulating mRNA translation. RNA elements in introns and exons are known to function as splicing enhancers or silencers during the splicing process from pre-mRNA to mature mRNA..This book provides case studies of RNA binding proteins that reg
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Stefanie Gerstberger,Markus Hafner,Manuel Ascano,Thomas Tuschlevolution rates (EC low and NEC high), level of total reductants, including glutathione (EC low and NEC high), and protein synthesis rates (EC high and NEC low). Conifer somatic embryos contained proplastids closely resembling those found in early zygotic embryos. On proliferation medium in the ligh
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Ling-Ling Chen,Jing Crystal Zhaoation development. The list includes the requirement of donor cell-nuclear remodeling, disposal of donor cell organelles, the possibility of heteroplasmy (i. e. , presence of mixed mitochondrial genomes) and altered mode of oocyte activation. Thanks to seminal contributions of my distinguished colle
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Rachel Soemedi,Hugo Vega,Judson M. Belmont,Sohini Ramachandran,William G. Fairbrotherenable to the oocyte reprogramming by the exogenous expression of human .. Given that the protamine also provides natural protection against dehydration stress, we have combined the cell protaminization and lyophilization protocols. This chapter comprehensively describes the protocol for somatic cel
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