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Titlebook: Symposium in Immunology VI; Tumor Immunology Martha M. Eibl,Christoph Huber,Ulrich Wahn Conference proceedings 1997 Springer-Verlag Berlin

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978-3-540-61755-6Springer-Verlag Berlin Heidelberg 1997
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CD95-Associating Signaling Moleculesvant for apoptosis might code for death or survival ligands and their receptors, or a cascade of signaling molecules. Such signaling molecules might be connected to second messengers and bridge membrane events to transcription factors and gene expression. Gene products might then either stimulate or block apoptosis.
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The Use of HLA Transgenic Mice in Identifying and Targeting Human Tumor Cell Antigensf tumor-infiltrating lymphocytes (TILs) has led to the identification of a series of melanoma specific antigens [1–4]. Although tissue-specific, these are of value due to their expression in tumors from different patients, thereby raising the possibility of a general immunotherapy or vaccine approach to stimulate the immune system.
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Towards the Development of Immunogenic Colon Cancer Cells for Immunotherapynosuppression which are exerted by tumor cells as soluble inhibitory activities. One must expect that both mechanisms play a role in the interaction between malignant tissue and the host immune system.
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