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Titlebook: Structure and Function of Membrane Proteins; Ingeborg Schmidt-Krey,James C. Gumbart Book 2021 Springer Science+Business Media, LLC, part o

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发表于 2025-3-21 19:08:16 | 显示全部楼层 |阅读模式
书目名称Structure and Function of Membrane Proteins
编辑Ingeborg Schmidt-Krey,James C. Gumbart
视频video
概述Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Structure and Function of Membrane Proteins;  Ingeborg Schmidt-Krey,James C. Gumbart Book 2021 Springer Science+Business Media, LLC, part o
描述This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize membrane proteins within different phospholipid bilayers, direction on functional studies, and approaches to determine the structures of membrane proteins. Detailed experimental steps for specific membrane proteins with critical notes allow the protocols to be modified to different systems. Written for the highly successful .Methods in Molecular Biology. series, chapters include the kind of practical information and implementation advice that leads to excellent, reproducible results. .Authoritative and up-to-date, .Structure and Function Studies of Membrane Proteins. serves as an ideal guide for biologists, biochemists, and biophysicists striving to furtherunderstand these essential proteins and their many biological roles..
出版日期Book 2021
关键词Over-expression; Phospholipid bilayers; Protein purification; Functional studies; Protein structure
版次1
doihttps://doi.org/10.1007/978-1-0716-1394-8
isbn_softcover978-1-0716-1396-2
isbn_ebook978-1-0716-1394-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2021
The information of publication is updating

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Structure Determination of Membrane Proteins Using X-Ray Crystallography,onsibilities include mediating cell signaling, nutrient import, waste export, cellular communication, trafficking, and immunity. For their critical role in many cellular processes, membrane proteins serve as targets for up to 50% of drugs currently on the market and remain primary targets in new the
发表于 2025-3-23 01:39:44 | 显示全部楼层
Studying Membrane Protein Structures by MicroED,pically grow crystals that are tens to hundreds of microns in size for X-ray crystallography. But membrane protein crystals often grow crystals that are too small for X-ray diffraction and yet too large for MicroED. These crystals are often formed in thick, viscous media that challenge traditional c
发表于 2025-3-23 08:24:02 | 显示全部楼层
Single-Particle Cryo-EM of Membrane Proteins,This trend will be further accelerated through the continuous software and method developments and the increasing availability of imaging centers, which will open cryo-EM to a wide array of researchers with their diverse scientific goals and questions. Especially for structural biology of membrane p
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