Titlebook: Squamous cell Carcinoma; Molecular Therapeuti Saman Warnakulasuriya,Zakir Khan Book 2017 Springer Science+Business Media B.V. 2017 Squamous

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p53 in Head and Neck Squamous Cell Carcinoma,factors associated with HNSCC are smoking, alcohol, and human papillomavirus (HPV). p53, a transcriptional factor, is the most commonly mutated protein in HNSCC and plays an important and early role in tumorigenesis. The chapter highlights the story of p53 in the progression and management of HNSCC.

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,Survivin as a Therapeutic Target in Squamous Cell Carcinoma,bition of apoptosis. As like other cancers, most of the SCCs also overexpress survivin gene. Tumors overexpressing survivin generally bear a poor prognosis and are associated with resistance to therapy. The differential expression of survivin in cancer versus normal tissues makes it a useful tool in

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MicroRNA: Utility as Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma, cell carcinomas. The majority of this research effort has focussed on microRNA, a class of small RNA able to regulate the expression of protein coding targets which frequently show aberrant expression patterns in cancer. Owing to their ready detection in bodily fluids, including saliva, interest ha

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