书目名称 | Squamous cell Carcinoma |
副标题 | Molecular Therapeuti |
编辑 | Saman Warnakulasuriya,Zakir Khan |
视频video | http://file.papertrans.cn/876/875116/875116.mp4 |
概述 | Contents of the book are up-to-date and cover material on almost all the aspects of molecular biology of cancer with special emphasis on SCC.The book should be a compromise between a generalized and a |
图书封面 |  |
描述 | .This edited volume is about novel targeted therapies for the treatment of advanced neoplasms of the head and neck (HNSCC) with particular reference to oral squamous cell carcinomas and covers specific fields of cancer genetics and genomics for personalized medicine...The landmark studies from the HNSCC Cancer Genome Anatomy (TCGA) and the cancer Genome Atlas 2015 have revealed the multiplicity and diversity of genetic alterations in HNSCC. This remarkable body of information has elucidated novel druggable targets (eg. EGFR, mTOR, p53, survivin and. .aberrant microRNA) for therapeutic interventions in head and neck cancer...Readers will discover the importance of the biology and pathology of squamous cell carcinomas, the role of cancer stem cells and other factors that contribute to resistance to curative therapies such as hypoxia. We present an in-depth analysis of the HNSCC oncogenome describing the distinct molecular alterations in squamous cell carcinomas, which participate in specific molecular pathways whose dysregulation may contribute to most HNSCC cases. Final chapters of the book elucidate how these important cancer-driving molecular events and molecular pathways could be |
出版日期 | Book 2017 |
关键词 | Squamous-cell carcinoma; Molecular carcinogenesis; Molecular therapeutics and diagnostics; Apoptotic ta |
版次 | 1 |
doi | https://doi.org/10.1007/978-94-024-1084-6 |
isbn_softcover | 978-94-024-1485-1 |
isbn_ebook | 978-94-024-1084-6 |
copyright | Springer Science+Business Media B.V. 2017 |