| 书目名称 | Short-Term Tests for Chemical Carcinogens |
| 编辑 | H. F. Stich (Head),R. H. C. San (Chief) |
| 视频video | |
| 丛书名称 | Topics in Environmental Physiology and Medicine |
| 图书封面 |  |
| 描述 | The recent surge of interest in designing, validating, and implementing short-term tests for carcinogens has been spurred by the fairly convincing correlation be tween the carcinogenicity and mutagenicity of chemicals and physical agents and by the assumption that DNA alteration, mutations, and chromosome aberrations are somehow involved in neoplastic transformation. Moreover, it has been tacitly assumed that the mutagenic capacity alone of compounds would induce regulatory agencies to pass rules for their removal from the environment and would lead the public to avoid them. The actual response, however, is quite different. Governmental departments shy away from making any decisions on the basis of in vitro test systems. The public at large is becoming irritated by daily an nouncements that many of their cherished habits could adversely affect their health. Industry appears to feel threatened and may reduce its search for new beneficial chemicals. The reluctance to accept wholeheartedly the mutagenicity tests for the detection of carcinogens is partly due to uncertainty about the in volvement of mutations in neoplastic transformation, partly due to the present difficulty of extr |
| 出版日期 | Conference proceedings 1981 |
| 关键词 | Calcium; DNA; Krebserregender Stoff; Mutagene; Mutation; Nucleotide |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4612-5847-6 |
| isbn_softcover | 978-1-4612-5849-0 |
| isbn_ebook | 978-1-4612-5847-6Series ISSN 0172-6048 |
| issn_series | 0172-6048 |
| copyright | Springer-Verlag New York Inc. 1981 |
发表于 2025-3-21 19:17:16
